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1

Induction therapy with the selective interleukin-23 inhibitor risankizumab in patients with moderate-to-severe Crohn's disease: a randomised, double-blind, placebo-controlled phase 2 study

Feagan, Brian G, Sandborn, William J, D'Haens, Geert, Panés, Julián, Kaser, Arthur, Ferrante, Marc, Louis, Edouard, Franchimont, Denis, Dewit, Olivier, Seidler, Ursula, Kim, Kyung-Jo, Neurath, Markus

Journal:

Year:

2017

Language:

english

File:

PDF, 992 KB

english, 2017

2

Ca2+/calmodulin-dependent protein kinase II isoenzymes γ and δ are both present in H+/K+-ATPase-containing rabbit gastric tubulovesicles

Michael Fährmann, Petra Jacob, Ursula Seidler, Martin Osterhoff, Matthias Möhlig, Andreas Pfeiffer

Journal:

Year:

1999

Language:

english

File:

PDF, 366 KB

english, 1999

3

cAMP-dependent and cholinergic regulation of the electrogenic intestinal/pancreatic Na+/HCO3-cotransporter pNBC1 in human embryonic kidney (HEK293) cells

Oliver Bachmann, Kristin Franke, Haoyang Yu, Brigitte Riederer, Hong C Li, Manoocher Soleimani, Michael P Manns, Ursula Seidler

Journal:

BMC Cell Biology

Year:

2008

Language:

english

File:

PDF, 1.10 MB

english, 2008

4

The role of cGMP-cGKI-signaling for duodenal bicarbonate secretion

Beate Spiessberger, Dieter Saur, Ursula Seidler, Anurag K Singh, Robert Lukowski, Franz Hofmann

Journal:

BMC Pharmacology

Year:

2011

Language:

english

File:

PDF, 97 KB

english, 2011

5

The role of cGMP-cGKI-signaling for duodenal bicarbonate secretion

Beate Spiessberger, Pascal Weinmeister, Franz Hofmann, Claudia Werner, Dieter Saur, Ursula Seidler, Wen Zheng, Jens Schlossmann, Robert Lukowski

Journal:

BMC Pharmacology

Year:

2009

Language:

english

File:

PDF, 74 KB

english, 2009

6

Cytoprotective effects of acidosis via heat shock protein HSP27 against the anticancer drug doxorubicin

Anurag Kumar Singh, Michael P. Manns, Ursula Seidler

Journal:

Cellular and Molecular Life Sciences

Year:

2011

Language:

english

File:

PDF, 598 KB

english, 2011

7

Down regulation of small intestinal ion transport in PDZK1- (CAP70/NHERF3) deficient mice

Jutta Hillesheim, Brigitte Riederer, Biguang Tuo, Mingmin Chen, Michael Manns, Jürg Biber, Chris Yun, Olivier Kocher, Ursula Seidler

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2007

Language:

english

File:

PDF, 390 KB

english, 2007

8

Sodium and chloride absorptive defects in the small intestine in Slc26a6 null mice

Ursula Seidler, Ingrid Rottinghaus, Jutta Hillesheim, Mingmin Chen, Brigitte Riederer, Anja Krabbenhöft, Regina Engelhardt, Martin Wiemann, Zhaouhui Wang, Sharon Barone, Michael P. Manns, Manoocher So

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2008

Language:

english

File:

PDF, 454 KB

english, 2008

9

Differential expression and regulation of AE2 anion exchanger subtypes in rabbit parietal and mucous cells

Heidi Rossmann, Oliver Bachmann, Zhuo Wang, Gary E. Shull, Brigitte Obermaier, Alan Stuart-Tilley, Seth L. Alper, Ursula Seidler

Journal:

The Journal of Physiology

Year:

2001

Language:

english

File:

PDF, 512 KB

english, 2001

10

Differential activation of the HCO3- conductance through the cystic fibrosis transmembrane conductance regulator anion channel by genistein and forskolin in murine duodenum

Biguang Tuo, Guorong Wen, Ursula Seidler

Journal:

British Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 545 KB

english, 2009

11

Acta Physiologica symposium: acid-base transporters and epithelial electrolyte transport

Journal:

Acta Physiologica

Year:

2011

Language:

english

File:

PDF, 39 KB

english, 2011

12

Expression and Function of Na+HCO3− Cotransporters in the Gastrointestinal Tract

URSULA SEIDLER, HEIDI ROSSMANN, PETRA JACOB, OLIVER BACHMANN, STEPHANIE CHRISTIANI, GEORG LAMPRECHT, MICHAEL GREGOR

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 4.80 MB

english, 2000

13

Three 5′-Variant mRNAs of Anion Exchanger AE2 in Stomach and Intestine of Mouse, Rabbit, and Rat

HEIDI ROSSMANN, SETH L. ALPER, MANUELA NADER, ZHUO WANG, MICHAEL GREGOR, URSULA SEIDLER

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 6.72 MB

english, 2000

14

The Role of the NHERF Family of PDZ Scaffolding Proteins in the Regulation of Salt and Water Transport : Lessons Learned from Knockout Mice

Ursula Seidler, Anurag Kumar Singh, Ayhan Cinar, Mingmin Chen, Jutta Hillesheim, Boris Hogema, Brigitte Riederer

Journal:

Annals of the New York Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 149 KB

english, 2009

15

The gastric H,K-ATPase blocker lansoprazole is an inhibitor of chloride channels

Andreas Schmarda, Patrick Dinkhauser, Martin Gschwentner, Markus Ritter, Johannes Fürst, Elke Scandella, Ewald Wöll, Andreas Laich, Heidi Rossmann, Ursula Seidler, Florian Lang, Markus Paulmichl

Journal:

British Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 455 KB

english, 2000

16

Different actions of protein kinase C isoforms α and ε on gastric acid secretion

Michael Fährmann, Marc Kaufhold, Timo Rieg, Ursula Seidler

Journal:

British Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 271 KB

english, 2002

17

Protein kinase C-α attenuates cholinergically stimulated gastric acid secretion of rabbit parietal cells

Michael Fährmann, Marc Kaufhold, Andreas F Pfeiffer, Ursula Seidler

Journal:

British Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 358 KB

english, 2003

18

Knockout mouse models for intestinal electrolyte transporters and regulatory PDZ adaptors: new insights into cystic fibrosis, secretory diarrhoea and fructose-induced hypertension

Ursula Seidler, Anurag Singh, Mingmin Chen, Ayhan Cinar, Oliver Bachmann, Wen Zheng, Jian Wang, Sunil Yeruva, Brigitte Riederer

Journal:

Experimental Physiology

Year:

2009

Language:

english

File:

PDF, 504 KB

english, 2009

19

NHE3 inhibition by cAMP and Ca2+ is abolished in PDZ-domain protein PDZK1-deficient murine enterocytes

Ayhan Cinar, Mingmin Chen, Brigitte Riederer, Oliver Bachmann, Martin Wiemann, Michael Manns, Olivier Kocher, Ursula Seidler

Journal:

The Journal of Physiology

Year:

2007

Language:

english

File:

PDF, 511 KB

english, 2007

20

KCNQ1 is the luminal K+ recycling channel during stimulation of gastric acid secretion

Penghong Song, Stephanie Groos, Brigitte Riederer, Zhe Feng, Anja Krabbenhöft, Adam Smolka, Ursula Seidler

Journal:

The Journal of Physiology

Year:

2009

Language:

english

File:

PDF, 671 KB

english, 2009

21

Adrenaline-induced colonic K+ secretion is mediated by KCa1.1 (BK) channels

Mads V. Sørensen, Matthias Sausbier, Peter Ruth, Ursula Seidler, Brigitte Riederer, Helle A. Praetorius, Jens Leipziger

Journal:

The Journal of Physiology

Year:

2010

Language:

english

File:

PDF, 933 KB

english, 2010

22

Molecular Mechanisms of Disturbed Electrolyte Transport in Intestinal Inflammation

URSULA SEIDLER, HENRIKE LENZEN, AYHAN CINAR, TESFAYE TESSEMA, ANDRÉ BLEICH, BRIGITTE RIEDERER

Journal:

Annals of the New York Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 333 KB

english, 2006

23

Rescue of epithelial HCO3− secretion in murine intestine by apical membrane expression of the cystic fibrosis transmembrane conductance regulator mutant F508del

Fang Xiao, Junhua Li, Anurag Kumar Singh, Brigitte Riederer, Jiang Wang, Ayesha Sultan, Henry Park, Min Goo Lee, Georg Lamprecht, Bob J. Scholte, Hugo R. De Jonge, Ursula Seidler

Journal:

The Journal of Physiology

Year:

2012

Language:

english

File:

PDF, 376 KB

english, 2012

24

Genistein stimulates duodenal HCO3− secretion through PI3K pathway in mice

Biguang Tuo, Guorong Wen, Penghong Song, Jingyu Xu, Xuemei Liu, Ursula Seidler, Hui Dong

Journal:

European Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.14 MB

english, 2011

25

CaMKII is activated and translocated to the secretory apical membrane during cholinergically conveyed gastric acid secretion

Michael Fährmann, Alexander Heinzmann, Ursula Seidler

Journal:

Cellular Signalling

Year:

2002

Language:

english

File:

PDF, 338 KB

english, 2002

26

Lactate flux in astrocytes is enhanced by a non-catalytic action of carbonic anhydrase II

Malin H. Stridh, Marco D. Alt, Sarah Wittmann, Hella Heidtmann, Mayank Aggarwal, Brigitte Riederer, Ursula Seidler, Gunther Wennemuth, Robert McKenna, Joachim W. Deitmer, Holger M. Becker

Journal:

The Journal of Physiology

Year:

2012

Language:

english

File:

PDF, 1.53 MB

english, 2012

27

Na+/HCO3− cotransport and expression of NBC1 and NBC2 in rabbit gastric parietal and mucous cells

Heidi Rossmann, Oliver Bachmann, Dorothee Vieillard–Baron, Michael Gregor, Ursula Seidler

Journal:

Gastroenterology

Year:

1999

Language:

english

File:

PDF, 191 KB

english, 1999

28

Expression of the C-terminal tail of DRA (down regulated in adenoma) as a recombinant antigen and to study protein-protein-interactions

Georg Lamprecht, Elena Lin Wu, Michael Gregor, Ursula Seidler

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 202 KB

english, 2000

29

Apical CL-/HCO3−−exchange is involved in basal but not agonist-stimulated rabbit duodenal HCO3− secretion

Stephanie Christiani, Michael Walter, Michael Gregor, Ursula Seidler

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 179 KB

english, 2000

30

The AE2 subtypes are differentially expressed and regulated in rabbit parietal and mucous cells

Heidi Rossmann, Oliver Bachmann, Zhuo Wang, Wolf-Christian Siegel, Barbara Seidler, Dorothee Vielliard-Baron, Michael Gregor, Gary E. Shull, Ursula Seidler

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 179 KB

english, 2000

31

Identification of a basolateral Cl-/HCO3- exchanger specific to gastric parietal cells

Snezana Petrovic, Xie Ju, Sharon Barone, Ursula Seidler, Juha Kere, Manoocher Soleimani

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 167 KB

english, 2003

32

Nhe2 is predominantly crypt-localized in murine proximal colon and its lack causes an anion secretory defect in NHE2-/- mice

Oliver Bachmann, Markus Rapedius, Heidi Rossmann, Katrin Wuechner, Patrick J. Schultheis, Gary E. Shull, Ursula Seidler

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 187 KB

english, 2003

33

845 Severe Downregulation of the NHE3 Adapterprotein Pdzk1 (NHERF3) in Colonic Mucosa of Patients with Active IBD - Implications for the Dysregulation of Salt and Water Transport

Katja Rode, Brigitte Riederer, Oliver Bachmann, Henrike Lenzen, Jochen Wedemeyer, Michael P. Manns, Ursula E. Seidler

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 67 KB

english, 2008

34

749 Nherf2 Is Necessary for Basal and All Second Messenger Regulation of NHE3 Activity in Intact Mouse Ileal Na Absorptive Cells

Rakhilya Murtazina, Olga Kovbasnjuk, Yueping Chen, Boris M. Hogema, Ursula E. Seidler, Edward J. Weinman, Hugo de Jonge, Mark Donowitz

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 70 KB

english, 2008

35

927 Role of Carbonic Anhydrase II in the Murine Duodenal Secretory Response to CO2, Secretagogues, and Mucosal Acidification

Markus Sjöblom, Anurag K. Singh, Anja Krabbenhöft, Brigitte Riederer, Michael P. Manns, Gerolf Gros, Ursula E. Seidler

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 70 KB

english, 2008

36

HCO3 secretion in rabbit gallbladder: Molecular mechanisms and regulation

Stefanie Christiani, Heidi Rossmann, Michael Gregor, Ursula Seidler

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 219 KB

english, 2001

37

787 Deletion of the Chloride/Base Exchanger Slc26a7 Impairs Gastric Acid Secretion and Causes Distal Renal Tubular Acidosis

Jie Xu, Penghong Song, Suguru Nakamura, Marian L. Miller, Sharon Barone, Seth L. Alper, Hassane Amlal, Ursula Seidler, Manoocher Soleimani

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 73 KB

english, 2009

38

881 The Slc2a5 (Glut5) Is Essential for the Absorption of Fructose in the Intestine and Generation of Fructose-Induced Hypertension

Sharon Barone, Stacey J. Fussell, Anurag K. Singh, Jie Xu, Hassane Amlal, Ursula E. Seidler, Jian Zuo, Manoocher Soleimani

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 52 KB

english, 2009

39

885 Preserved Abundance But Functional Dysregulation of Na+/H+ Exchanger Isoform NHE3 in the Small and Large Intestine in CD45RBhigh Transfer Colitis Mice with Diarrhea

Sunil Yeruva, Julia Goldstein, Maria Lünnemann, Mingmin Chen, Anurag K. Singh, Brigitte Riederer, Marcus Gereke, Dunja Bruder, Michael P. Manns, Ursula E. Seidler

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 71 KB

english, 2009

40

1061 Gastric KNCQ1 Channels Provide Luminal K+ to the H+/K+ ATPase, Whereas Kir 4.1 Channels Are Involved in Secretory Membrane Recycling

Penghong Song, Stephanie Groos, Brigitte Riederer, Zhe Feng, Anja Krabbenhöft, Michael P. Manns, Adam J. Smolka, Susan J. Hagen, Clemens Neusch, Ursula Seidler

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 50 KB

english, 2009

41

1011 SLC26 Anion Transporters Involvement in Luminal Acid-Activated Murine Duodenal HCO3− Secretion In Vivo

Anurag K. Singh, Brigitte Riederer, Anja Krabbenhoeft, Janina Bonhagen, Brigitte Rausch, Regina Engelhardt, Manoocher Soleimani, Ursula Seidler

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 52 KB

english, 2010

42

Membrane Expression of Deltaf508 Mutant Increases Epithelial HCO3- Secretion via Functional Cl-/HCO3-Exchanger(S)

Fang Xiao, Junhua Li, Ayesha Sultan, Jian Wang, Brigitte Riederer, Regina Engelhardt, Brigitte Rausch, Georg Lamprecht, Hugo de Jonge, Bob J. Scholte, Ursula Seidler

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 39 KB

english, 2011

43

Role of Na+HCO3− Cotransporter NBC1, Na+/H+ Exchanger NHE1, and Carbonic Anhydrase in Rabbit Duodenal Bicarbonate Secretion

Petra Jacob*, Stefanie Christiani*, Heidi Rossmann*, Georg Lamprecht*, Dorothee Vieillard-Baron*, Robert Müller†, Michael Gregor*, Ursula Seidler*

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 459 KB

english, 2000

44

Down-regulated in adenoma mediates apical Cl-/HCO3− exchange in rabbit, rat, and human duodenum

Petra Jacob, Heidi Rossmann, Georg Lamprecht, Alexandra Kretz, Christina Neff, Elena Lin-Wu, Michael Gregor, David A. Groneberg, Juha Kere, Ursula Seidler

Journal:

Gastroenterology

Year:

2002

Language:

english

File:

PDF, 4.00 MB

english, 2002

45

Involvement of the Anion Exchanger SLC26A6 in Prostaglandin E2- but not Forskolin-Stimulated Duodenal HCO3− Secretion

BiGuang Tuo, Brigitte Riederer, Zhaohui Wang, William H. Colledge, Manoocher Soleimani, Ursula Seidler

Journal:

Gastroenterology

Year:

2006

Language:

english

File:

PDF, 479 KB

english, 2006

46

Localization, Trafficking, and Significance for Acid Secretion of Parietal Cell Kir4.1 and KCNQ1 K+ Channels

Marc–André Kaufhold, Anja Krabbenhöft, Penghong Song, Regina Engelhardt, Brigitte Riederer, Michael Fährmann, Nikolaj Klöcker, Winfried Beil, Michael Manns, Susan J. Hagen, Ursula Seidler

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 2.63 MB

english, 2008

47

Lysophosphatidic Acid Stimulates the Intestinal Brush Border Na+/H+ Exchanger 3 and Fluid Absorption via LPA5 and NHERF2

Songbai Lin, Sunil Yeruva, Peijian He, Anurag Kumar Singh, Huanchun Zhang, Mingmin Chen, Georg Lamprecht, Hugo R. de Jonge, Ming Tse, Mark Donowitz, Boris M. Hogema, Jerold Chun, Ursula Seidler, C. Ch

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 1.39 MB

english, 2010

48

D-Glucose Acts via Sodium/Glucose Cotransporter 1 to Increase NHE3 in Mouse Jejunal Brush Border by a Na+/H+ Exchange Regulatory Factor 2–Dependent Process

Rong Lin, Rakhilya Murtazina, Boyoung Cha, Molee Chakraborty, Rafiquel Sarker, Tian–E. Chen, Zhihong Lin, Boris M. Hogema, Hugo R. de Jonge, Ursula Seidler, Jerrold R. Turner, Xuhang Li, Olga Kovbasnj

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 3.80 MB

english, 2011

49

The electroneutral Na+:HCO3− cotransporter NBCn1 is a major pHi regulator in murine duodenum

Mingmin Chen, Jeppe Praetorius, Wen Zheng, Fang Xiao, Brigitte Riederer, Anurag Kumar Singh, Nicole Stieger, Jian Wang, Gary E. Shull, Christian Aalkjaer, Ursula Seidler

Journal:

The Journal of Physiology

Year:

2012

Language:

english

File:

PDF, 1.41 MB

english, 2012

50

Pseudomonas aeruginosareduces the expression of CFTR via post-translational modification of NHERF1

Rubino, Rosa, Bezzerri, Valentino, Favia, Maria, Facchini, Marcella, Tebon, Maela, Singh, Anurag Kumar, Riederer, Brigitte, Seidler, Ursula, Iannucci, Antonio, Bragonzi, Alessandra, Cabrini, Giulio, R

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2014

Language:

english

File:

PDF, 694 KB

english, 2014

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